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Patients treated for 12 weeks were spared the expense and inconvenience of extended treatment and still had a high response rate. The shorter regimen was associated with fewer side effects and, consequently, less frequent withdrawals from therapy. Moreover, patients assigned to 12 weeks of treatment were less likely to require a reduction in the dose of peginterferon alfa-2b or of ribavirin. The proportion of patients with relapse was higher among those treated for 12 weeks than those treated for the standard 24 weeks. However, 90 percent of patients with a relapse after 12 weeks of treatment had a response after an additional 24-week course of therapy. Therefore, even taking into consideration the rate falmec pg allegra 1430 am relapse, treatment for 12 weeks rather than 24 weeks appears to be appropriate for patients with an early response. These results are consistent with the results of an uncontrolled Norwegian study in which 85 of 95 patients (89 percent) with HCV genotype 2 or 3 had a response 14 weeks after peginterferon alfa-2b and ribavirin therapy was initiated. 17 That investigation and our study differed in the weekly dose eona drachentochter rezension allegra peginterferon alfa-2b: the Norwegian study administered 1.

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